No undersible side-effect has been noticed among humans :

• During studies conducted with a single dose of Lactium® 7 times superior to the advisable dose of 150 mg a day there was no memory loss, no drowsiness, no disinhibition and was not habit forming (unwanted side- effects traditionally observed with anxiolitics).
  
• When using the Hopkins List, 58 questions focusing on psychosomatic reactions, TOC, anxiety and depression, no psychological or pscho-somatic side effects were observed.
  
• When using the Thayer Questionnaire, which examines alertness and muscular reactiviy, no side effects to either were found.

No toxic effect has been observed during toxicological studies of Lactium® :

• no toxicity after ingesting a strong dose of Lactium® (2000 mg/kg)
  
• no toxicity (neither acute nor chronic) even when taking Lactium® at a dose of 1000 mg/kg each day for 14 days, 28 days and 91 days.
  
• no teratogenic effect: no malformations, neither during gestation, nor post partum.
  
• no cytotoxicity (cellular death)
  
• No mutagen effect: no cellular mutation or deterioration

Lactium® is not problematic for lactose intolerant people.

It has been shown that people with severe lactose intolerance can ingest up to 5g of lactose per day. Given that the lactose content in Lactium® does not exceed 1% and the recommended dose of Lactium® is 150mg per day, taking Lactium® poses no risk for lactose intolerant people.

All tests conducted to evaluate Lactium®'s toxicity followed OCDE recommendations (Organisation for Economic Co-operation and Development).